Researcher

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Kontakt: Dr. Lorenzo Corsini

PhagoMed is looking for a TALENTED (JUNIOR) RESEARCHER TO JOIN OUR TEAM (m/f/d) in Vienna, Austria

Do you want to be part of developing a high-profile antibiotics alternative and help drive the research into new bacterial lysins – together with an experienced and motivated team and a network of leading physicians?

Then apply for our current vacancy as

(JUNIOR) RESEARCHER (m/f/d) 

WHAT WE ARE LOOKING FOR

MANDATORY REQUIREMENTS

  • Completed university degree in biology, molecular biology or a related subject.
  • At least 2 years of laboratory experience
  • At least 6 months research experience in microbiology incl. handling of pathogenic bacteria and working in a BSL-2 laboratory
  • Interest in targeted pharmaceutical development;
  • Interest in working in a team of highly skilled and motivated professionals
  • Fluent in English

WELCOME ADD-ON QUALIFICATIONS

  • Experience with protein expression and purification
  • Molecular cloning, combinatorial methods, library screening
  • Experience in pharmaceutical research in a start-up/ company
  • Experience in working in a controlled environment (GxP)
  • Experience in operating equipment like pipetting robots,
  • Experience in genomic analyses

ROLE DESCRIPTION

  • Execute series of experiments to support the developmental program, all following established protocols, including:
    • Expression and purification of proteins for scientific research
    • Activity testing of lysins against bacterial strains (BSL-2 strains like Gardnerella, others)
    • Directed evolution of enzymes
    • Biofilm assays
    • Isolation of bacteria from human and environmental samples
  • Actively participate in designing the required experiments and improving the established protocols, as part of the lab team
  • Develop capabilities in operating advanced equipment, including programming of a pipetting robot, documenting key methods
  • Documentation of results according to the PhagoMed Quality Standards (non-GLP but close), to ensure the quality of results and their documentation are acceptable to regulatory authorities, working towards a human clinical trial application;
  • Establish research processes according to the latest microbiological technology developments (e.g. robotics and genomic data);
  • Maintain laboratory infrastructure together with the team, including purchasing of reagents and equipment, in-house preparation of materials like media and agar plates

 

WHAT WE OFFER

  • Become part of developing a new asset class in anti-infectives
  • Take responsibility for specific parts of the development program and work together with highly experienced researchers in executing the development plan
  • Pioneer new methods and processes to industrialize key research techniques
  • Be part of a highly motivated, multinational and fun team that believes phage-based therapies can be part of the solution to the global antibiotics crisis
  • A competitive compensation package that reflects the qualifications and seniority of the candidate. Due to legal requirements, we are required to state that the minimum salary for the position of Junior Researcher is a monthly salary of EUR 2.200,-- gross.

WHAT MOTIVATES US?

Antibiotics fail in many dimensions: many bacteria are resistant, they mostly don’t work on biofilms, and they disrupt the microbiome by non-selectively killing all bacteria. In contrast, phage endolysins lyse bacteria with a high selectiveness, while not harming the beneficial microbiome, even in biofilms, even when the bacteria are antibiotic resistant. We develop synthetic, improved variants of natural endolysins, to treat chronic or persistent bacterial infections. Our lead asset is PM-477, which we develop for the treatment of bacterial vaginosis (see article) There are many other diseases where patients could benefit from this emerging class of precision antimicrobials.

WHO AND WHAT IS PHAGOMED?

PhagoMed Biopharma GmbH is an Austrian biotech company focused on synthetic lysins against chronic indications with high medical need. The company has developed a proprietary platform to develop synthetic lysins for any bacterial pathogen by using a combination of in-silico prediction, synthetic assembly and directed evolution. Its development pipeline focuses on chronic bacterial infections where suppressive antibiotics fail to cure and frequently destroy the natural microbiomes. Its lead program, PM-477, is a novel breakthrough therapy for recurrent bacterial vaginosis.

Our Vision: To develop breakthrough therapies for chronic bacterial infections.

 

INTERESTED? PLEASE CONTACT US!

To submit your application, please click on the following link:

Online-Application

Please also feel free to reach out directly if you have specific questions:

Dr. Lorenzo Corsini,

Co-CEO | Science & Discovery, PhagoMed

contact@phagomed.com

 


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